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Enass Ali Alkhader

METHOD DEVELOPMENT AND VALIDATION OF
BTIPIVACAINE IN HT]MAN PLASMA AND THE
FEASABILITY TO BE APPLIED ON PREGNANT WOMEN
DURING LABOR
By
Enass Ali Alkhader
Supervisor
Prof. Tawfiq Arafat
Co-Supervisor
Dr. Wael Abu Dawih
A Thesis Submitted in Partial Fulfillment of the Requirements for the
Degree of Master of Science in Pharmaceutical Sciences at
Universitv of Petra
Faculty of Pharmacy and Medical Sciences
Amman-Jordan
June 2013
Method Development and Validation of Bupivacaine in
Human Plasma and the Feasibility to be Applied on Pregnant
Women During Labor
By
Enass Ali Al-khader
A Thesis Submitted in Partial Fulfillment of the Requirements for the
Degree of Master of Science in Pharmaceutical Sciences at University of
Petra
Faculty of Pharmacy and Medical Sciences
Amman-Jordan
June 2013
DEDICATIONS
First and foremost, I dedicate my work to Allah, the Almighty, lor he empowered
me the strength to persist all the way long, and granted me the blessing to finish
this thesis the wav it is.
To you my father; making you proud has always been my first aim, you have always
been my source of encouragement, support and inspiration throughout my whole life,
thank you for teaching me the impossible is nothing, with you by my side, I can reach
the stars.
To my beloved mother; you lend me a hand to stand up when everything seemed
like falling apart, without your full heart prayers I would have never achieved any
of this.
To my dear husband, Emad, thank you for your understanding and encouragement in
my moments ofcrisis, I would happily consider rny success as yours.
My brothers, sisters and friends deserve my wholehearted thanks as well.