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Ala'a Rakan Al-Fayez

Validation and Determination of Glimepiride, Atorvastatin
and Amlodipine in Dosage Form and Plasma by Using High
Performance Liquid Chromatography Method
By
Ala'a Rakan Al-Fayez
A Thesis Submitted in
Partial Fulfillment of the
Requirements for the Degree of
Master of Science
in Pharmaceutical Sciences
at
University of Petra
Faculty of Pharmacy and Medical Sciences
Amman-Jordan
June 2014
II
Validation and determination of Glimepiride, Atorvastatin and
Amlodipine in dosage form and plasma by using HPLC method
By
Ala'a Rakan Al-Fayez
A Thesis Submitted in Partial Fulfillment of the Requirements for
the Degree of
Master of Science
in Pharmaceutical Sciences
at University of Petra
Faculty of Pharmacy and Medical Sciences
Amman-Jordan
June 2014
 
III
Dedicated to…….
The soul of my father Rakan Mohammad Al-fayez
who had been a wonderful father and teacher to me, may his soul rest in
peace.
IV
Acknowledgement
I would like to thank my supervisor Dr. Wael Abu Dayyih for his great help and
guidance during all stages of my work, Dr.Eyad Mallah for his support and guidance.
Special thanks go to my family of Dar Al Dawa (DAD) for all the efforts and support
throughout this study. My great thank to all members of the examination committee
for their efforts in evaluating this research. Many thanks go to Dr.Ghazi Al-Adwan
from DAD for his great help.