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Name : Mohammad Al-Natour

Academic Rank: Assistant Professor

Administrative Position : Dean Assistant for Quality Assurance

Office 8B-8147 Ext No 8147

Email : mohammad.alnatour@uop.edu.jo

Specialization: Pharmaceutical Technology

Graduate Of: University of Nottingham

Qualification

Qualification	University	Country	Year
Bachelor	Philadelphia	Jordan	2010
Masters	Jordan University of Science and Technology	Jordan	2015
Ph.D	University of Nottingham	United Kingdom	2019

Journal Paper

Ali Alazzo, Mohammad Al-Natour, Keith Spriggs, Snjezana Stolnik, Amir Ghaemmaghami, dong-Hyun Kima and Cameron Alexander, " Investigating the intracellular effects of hyperbranched polycation–DNA complexes on lung cancer cells using LC-MS-based metabolite profiling " , "Molecular Omics",Vol.15,No., Royal society of chemistry, London, UK, 02/01/2019

Abstract:

Cationic polymers have emerged as a promising alternative to viral vectors in gene therapy. They are cheap to scale up, easy to functionalise and are potentially safer than viral vectors, however many are cytotoxic. The large number of polycations, designed to address the toxicity problem, raises a Download

Mohammad Ahmad Al-Natour, Ali Alazzo, Amir M Ghaemmaghami, Dong-Hyun Kim, Cameron Alexander, " LC-MS metabolomics comparisons of cancer cell and macrophage responses to methotrexate and polymer-encapsulated methotrexate " , "International Journal of Pharmaceutics: X",Vol.1,No., Elsevier, Lille cedex, France, 12/01/2019

Abstract:

Methotrexate (MTX) is a folate analogue antimetabolite widely used for the treatment of rheumatoid arthritis and cancer. A number of studies have shown that MTX delivered via nanoparticle carriers is more potent against cancer cells than free MTX, a phenomenon attributed to higher cellular uptake of Download

Cl?udia Martins, Veeren M. Chauhan, Amjad A. Selo, Mohammad Al-Natour, Jonathan W. Aylott and Bruno Sarmento, " Modelling protein therapeutic co-formulation and co-delivery with PLGA nanoparticles continuously manufactured by microfluidics " , "Reaction Chemistry & Engineering",Vol.5,No., The Royal Society of Chemistry, Massachusetts Institute of Technology, USA, 11/28/2019

Abstract:

Formulating protein therapeutics into nanoparticles (NPs) of poly(lactic-co-glycolic acid) (PLGA) provides key features such as protection against clearance, sustained release and less side effects by possible attachment of targeting ligands. These NPs also offer the potential for protein combinatio Download

Mohammad A. Al-Natour, Mohamed D. Yousif, Robert Cavanagh, Amjad Abouselo, Edward A. Apebende, Amir Ghaemmaghami, Dong-Hyun Kim, Jonathan W. Aylott, Vincenzo Taresco, Veeren M. Chauhan, and Cameron Al, " Facile Dye-Initiated Polymerization of Lactide−Glycolide Generates Highly Fluorescent Poly(lactic-co-glycolic Acid) for Enhanced Characterization of Cellular Delivery " , "ACS Macro Letters",Vol.9,No., American Chemical Society, Chicago, USA, 02/07/2020

Abstract:

Poly(lactic-co-glycolic acid) (PLGA) is a versatile synthetic copolymer that is widely used in pharmaceutical applications. This is because it is well-tolerated in the body, and copolymers of varying physicochemical properties are readily available via ring-opening polymerization. However, native PL Download

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